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Escaping the flatlands: new approaches to study dynamic assembly and activation of GPCR signaling complexes
Despite significant recent advances in molecular and structural studies of G protein-coupled receptors (GPCRs), understanding transmembrane signal transduction with chemical precision requires new approaches. Simple binary receptor-ligand or receptor-G protein complex models cannot describe adequate...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128647/ https://ncbi.nlm.nih.gov/pubmed/21497404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.03.004 |
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