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Raf Family Kinases: Old Dogs Have Learned New Tricks

First identified in the early 1980s as retroviral oncogenes, the Raf proteins have been the objects of intense research. The discoveries 10 years later that the Raf family members (Raf-1, B-Raf, and A-Raf) are bona fide Ras effectors and upstream activators of the ubiquitous ERK pathway increased th...

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Détails bibliographiques
Auteurs principaux: Matallanas, David, Birtwistle, Marc, Romano, David, Zebisch, Armin, Rauch, Jens, von Kriegsheim, Alexander, Kolch, Walter
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128629/
https://ncbi.nlm.nih.gov/pubmed/21779496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911407323
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