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Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS
Mitochondria manganese superoxide dismutase (SOD2) is an important antioxidant enzyme, deficiency of which is associated with various human diseases. The known primary regulation of SOD2 is through transcriptional activation. Here, we report that SOD2 is acetylated at Lys 68 and that this acetylatio...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128277/ https://ncbi.nlm.nih.gov/pubmed/21566644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.65 |
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