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Hierarchical phosphorylation of the translation inhibitor 4E-BP1

In most instances, translation is regulated at the initiation phase, when a ribosome is recruited to the 5′ end of an mRNA. The eIF4E-binding proteins (4E-BPs) interdict translation initiation by binding to the translation factor eIF4E, and preventing recruitment of the translation machinery to mRNA...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Gingras, Anne-Claude, Raught, Brian, Gygi, Steven P., Niedzwiecka, Anna, Miron, Mathieu, Burley, Stephen K., Polakiewicz, Roberto D., Wyslouch-Cieszynska, Aleksandra, Aebersold, Ruedi, Sonenberg, Nahum
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312813/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691836/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.912401
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