Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

Double-stranded RNAs can suppress expression of homologous genes through an evolutionarily conserved process named RNA interference (RNAi) or post-transcriptional gene silencing (PTGS). One mechanism underlying silencing is degradation of target mRNAs by an RNP complex, which contains ∼22 nt of siRN...

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Autori principali: Ketting, René F., Fischer, Sylvia E.J., Bernstein, Emily, Sijen, Titia, Hannon, Gregory J., Plasterk, Ronald H.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2001
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC312808/
https://ncbi.nlm.nih.gov/pubmed/11641272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.927801
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