Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: Implications for HIV-associated neurocognitive disorders

Up to 50% of long-term HIV infected patients, including those with systemically well-controlled infection, commonly experience memory problems and slowness, difficulties in concentration, planning, and multitasking. Deposition of Aβ plaques is also a common pathological feature of HIV infection. How...

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Detalhes bibliográficos
Main Authors: Giunta, Brian, Ehrhart, Jared, Obregon, Demian F, Lam, Lucy, Le, Lisa, Jin, JingJi, Fernandez, Francisco, Tan, Jun, Shytle, R Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128056/
https://ncbi.nlm.nih.gov/pubmed/21649911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-4-23
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