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GPCR oligomers in pharmacology and signaling

G protein-coupled receptors (GPCRs) represent one of the largest families of cell surface receptors, and are the target of more than half of the current therapeutic drugs on the market. When activated by an agonist, the GPCR undergoes conformational changes that facilitate its interaction with heter...

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Bibliographic Details
Main Author: González-Maeso, Javier
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128055/
https://ncbi.nlm.nih.gov/pubmed/21619615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-4-20
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