Site-specific protein modifications through pyrroline-carboxy-lysine residues

Pyrroline-carboxy-lysine (Pcl) is a demethylated form of pyrrolysine that is generated by the pyrrolysine biosynthetic enzymes when the growth media is supplemented with D-ornithine. Pcl is readily incorporated by the unmodified pyrrolysyl-tRNA/tRNA synthetase pair into proteins expressed in Escheri...

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Detalhes bibliográficos
Main Authors: Ou, Weijia, Uno, Tetsuo, Chiu, Hsien-Po, Grünewald, Jan, Cellitti, Susan E., Crossgrove, Tiffany, Hao, Xueshi, Fan, Qian, Quinn, Lisa L., Patterson, Paula, Okach, Linda, Jones, David H., Lesley, Scott A., Brock, Ansgar, Geierstanger, Bernhard H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127931/
https://ncbi.nlm.nih.gov/pubmed/21670250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105197108
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