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Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif
The three-disulfide inhibitor cystine knot (ICK) motif is a fold common to venom peptides from spiders, scorpions, and aquatic cone snails. Over a decade ago it was proposed that the ICK motif is an elaboration of an ancestral two-disulfide fold coined the disulfide-directed β-hairpin (DDH). Here we...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127888/ https://ncbi.nlm.nih.gov/pubmed/21670253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103501108 |
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