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Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold
The ICK (inhibitor cystine knot) defines a large superfamily of polypeptides with high structural stability and functional diversity. Here, we describe a new scorpion venom-derived K(+) channel toxin (named λ-MeuKTx-1) with an ICK fold through gene cloning, chemical synthesis, nuclear magnetic reson...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694633/ https://ncbi.nlm.nih.gov/pubmed/23721518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130052 |
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