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Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein
Argonaute proteins (AGOs) are essential effectors in RNA-mediated gene silencing pathways. They are characterized by a bilobal architecture, in which one lobe contains the N-terminal and PAZ domains and the other contains the MID and PIWI domains. Here, we present the first crystal structure of the...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127882/ https://ncbi.nlm.nih.gov/pubmed/21646546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103946108 |
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