Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein

Argonaute (AGO) proteins are core components of RNA-induced silencing complexes and have essential roles in RNA-mediated gene silencing. They are characterized by a bilobal architecture, consisting of one lobe containing the amino-terminal and PAZ domains and another containing the MID and PIWI doma...

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Bibliographic Details
Main Authors: Boland, Andreas, Tritschler, Felix, Heimstädt, Susanne, Izaurralde, Elisa, Weichenrieder, Oliver
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897117/
https://ncbi.nlm.nih.gov/pubmed/20539312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.81
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