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Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways

Signaling pathways essential for axon regeneration, but not for neuron development or function, are particularly well suited targets for therapeutic intervention. We find that the parallel PMK-3(p38) and KGB-1(JNK) MAPK pathways must be coordinately activated to promote axon regeneration. Axon regen...

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Bibliografiske detaljer
Main Authors: Nix, Paola, Hisamoto, Naoki, Matsumoto, Kunihiro, Bastiani, Michael
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127873/
https://ncbi.nlm.nih.gov/pubmed/21670305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104830108
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