Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

The specificity of ubiquitin-mediated protein degradation with regards to the selection of substrates to be polyubiquitinated has only been determined rather recently. Substrate targeting by the N-end rule and HECT (homology to E6AP carboxyl terminus) domain ubiquitin ligases occurs through substrat...

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Publié dans:	Genes Dev
Auteurs principaux:	Pfleger, Cathie M., Lee, Ethan, Kirschner, Marc W.
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 2001
Sujets:	Research Paper
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11562349/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.918201
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