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Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

The specificity of ubiquitin-mediated protein degradation with regards to the selection of substrates to be polyubiquitinated has only been determined rather recently. Substrate targeting by the N-end rule and HECT (homology to E6AP carboxyl terminus) domain ubiquitin ligases occurs through substrat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Pfleger, Cathie M., Lee, Ethan, Kirschner, Marc W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11562349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.918201
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