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Plasmodium falciparum var Gene Silencing Is Determined by cis DNA Elements That Form Stable and Heritable Interactions

Antigenic variation in the human malaria parasite Plasmodium falciparum depends on the transcriptional regulation of the var gene family. In each individual parasite, mRNA is expressed exclusively from 1 var gene out of ∼60, while the rest of the genes are transcriptionally silenced. Both modificati...

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Hlavní autoři: Swamy, Lakshmi, Amulic, Borko, Deitsch, Kirk W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127639/
https://ncbi.nlm.nih.gov/pubmed/21317310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00329-10
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