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Suppression of cap-dependent translation in mitosis

Cap-dependent translation is mediated by eIF4F, a protein complex composed of three subunits as follows: eIF4E, which recognizes the mRNA 5′ cap structure; eIF4A, an RNA-helicase; and eIF4G, a scaffolding protein that binds eIF4E, eIF4A, and the eIF4E-kinase Mnk1 simultaneously. eIF4E is hypophospho...

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Publicat a:Genes Dev
Autors principals: Pyronnet, Stéphane, Dostie, Josée, Sonenberg, Nahum
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312759/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11511540/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.889201
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