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Characterization of uracil-DNA glycosylase activity from Trypanosoma cruzi and its stimulation by AP endonuclease

The intracellular pathogen Trypanosoma cruzi is the etiological agent of Chagas’ disease. We have isolated a full-length cDNA encoding uracil-DNA glycosylase (UDGase), a key enzyme involved in DNA repair, from this organism. The deduced protein sequence is highly conserved at the C-terminus of the m...

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Publicat a:Nucleic Acids Res
Autors principals: Fárez-Vidal, M. Esther, Gallego, Cláribel, Ruiz-Pérez, Luis Miguel, González-Pacanowska, Dolores
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31275/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11266557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.7.1549
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