The Ogg1 protein of Saccharomyces cerevisiae: a 7,8-dihydro-8-oxoguanine DNA glycosylase/AP lyase whose lysine 241 is a critical residue for catalytic activity.

The OGG1 gene of Saccharomyces cerevisiae codes for a DNA glycosylase that excises 7,8-dihydro-8- oxoguanine (8-OxoG) and 2,6-diamino-4-hydroxy-5- N -methylformamidopyrimidine (Fapy) from damaged DNA. In this paper, we have analysed the substrate specificity and the catalytic mechanism of the Ogg1 p...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Girard, P M, Guibourt, N, Boiteux, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9241232/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.16.3204
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