An evolutionarily ‘young’ lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae

The DNA entry and exit points on the nucleosome core regulate the initial invasion of the nucleosome by factors requiring access to the underlying DNA. Here we describe in vivo consequences of eliminating a single protein–DNA interaction at this position through mutagenesis of histone H3 Lys 42 to a...

詳細記述

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書誌詳細
主要な著者: Hyland, Edel M., Molina, Henrik, Poorey, Kunal, Jie, Chunfa, Xie, Zhi, Dai, Junbiao, Qian, Jiang, Bekiranov, Stefan, Auble, David T., Pandey, Akhilesh, Boeke, Jef D.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2011
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127431/
https://ncbi.nlm.nih.gov/pubmed/21685365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2050311
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