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Inhibition of Cdh1–APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1

Exit from mitosis requires the degradation of regulatory proteins including the mitotic cyclins and securin through ubiquitination by the anaphase promoting complex (APC) bound to Cdc20 or Cdh1. Cdc20–APC is regulated through inhibition by the spindle assembly checkpoint protein MAD2. Knowledge of C...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Pfleger, Cathie M., Salic, Adrian, Lee, Ethan, Kirschner, Marc W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.897901
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