Inhibition of Cdh1–APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1

Exit from mitosis requires the degradation of regulatory proteins including the mitotic cyclins and securin through ubiquitination by the anaphase promoting complex (APC) bound to Cdc20 or Cdh1. Cdc20–APC is regulated through inhibition by the spindle assembly checkpoint protein MAD2. Knowledge of C...

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Pubblicato in:	Genes Dev
Autori principali:	Pfleger, Cathie M., Salic, Adrian, Lee, Ethan, Kirschner, Marc W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2001
Soggetti:	Research Communication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.897901
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