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MAD2B is an inhibitor of the anaphase-promoting complex

Anaphase-promoting complex (APC), a ubiquitin ligase, controls both sister chromatid separation and mitotic exit. The APC is activated in mitosis and G(1) by CDC20 and CDH1, and inhibited by the checkpoint protein MAD2, a specific inhibitor of CDC20. We show here that a MAD2 homolog MAD2B also inhib...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Genes Dev
Ngā kaituhi matua: Chen, James, Fang, Guowei
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Cold Spring Harbor Laboratory Press 2001
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459826/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.898701
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