MAD2B is an inhibitor of the anaphase-promoting complex
Anaphase-promoting complex (APC), a ubiquitin ligase, controls both sister chromatid separation and mitotic exit. The APC is activated in mitosis and G(1) by CDC20 and CDH1, and inhibited by the checkpoint protein MAD2, a specific inhibitor of CDC20. We show here that a MAD2 homolog MAD2B also inhib...
Guardat en:
| Publicat a: | Genes Dev |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.898701 |
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