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Autophagy in mammalian development and differentiation

It has been known for many decades that autophagy, a conserved lysosomal degradation pathway, is highly active during differentiation and development. However, until the discovery of the autophagy-related (ATG) genes in the 1990s, the functional significance of this activity was unknown. Initially,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mizushima, Noboru, Levine, Beth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127249/
https://ncbi.nlm.nih.gov/pubmed/20811354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb0910-823
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