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The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death

Autophagy is important for the degradation of bulk cytoplasm, long-lived proteins, and entire organelles. In lower eukaryotes, autophagy functions as a cell death mechanism or as a stress response during development. However, autophagy’s significance in vertebrate development, and the role (if any)...

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Detalhes bibliográficos
Main Authors: Cecconi, Francesco, Levine, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688784/
https://ncbi.nlm.nih.gov/pubmed/18804433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.08.012
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