Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferase

V(D)J recombination generates a remarkably diverse repertoire of antigen receptors through the rearrangement of germline DNA. Terminal deoxynucleotidyl transferase (TdT), a polymerase that adds random nucleotides (N regions) to recombination junctions, is a key enzyme contributing to this diversity....

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Purugganan, Mary M., Shah, Sundeep, Kearney, John F., Roth, David B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31272/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11266568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.7.1638
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