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How Do Thermophilic Proteins and Proteomes Withstand High Temperature?

We attempt to understand the origin of enhanced stability in thermophilic proteins by analyzing thermodynamic data for 116 proteins, the largest data set achieved to date. We compute changes in entropy and enthalpy at the convergence temperature where different driving forces are maximally decoupled...

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Autori principali: Sawle, Lucas, Ghosh, Kingshuk
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127178/
https://ncbi.nlm.nih.gov/pubmed/21723832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.05.059
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