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Cellular Proteomes Have Broad Distributions of Protein Stability
Biological cells are extremely sensitive to temperature. What is the mechanism? We compute the thermal stabilities of the whole proteomes of Escherichia coli, yeast, and Caenorhabditis elegans using an analytical model and an extensive database of stabilities of individual proteins. Our results supp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000515/ https://ncbi.nlm.nih.gov/pubmed/21156142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.036 |
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