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H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G(1) phase
Centromeres are key regions of eukaryotic chromosomes that ensure proper chromosome segregation at cell division. In most eukaryotes, centromere identity is defined epigenetically by the presence of a centromeric histone H3 variant CenH3, called CENP-A in humans. How CENP-A is incorporated and repro...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127096/ https://ncbi.nlm.nih.gov/pubmed/21738837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.2.15211 |
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