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H3.3 is deposited at centromeres in S phase as a placeholder for newly assembled CENP-A in G(1) phase

Centromeres are key regions of eukaryotic chromosomes that ensure proper chromosome segregation at cell division. In most eukaryotes, centromere identity is defined epigenetically by the presence of a centromeric histone H3 variant CenH3, called CENP-A in humans. How CENP-A is incorporated and repro...

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Autors principals: Dunleavy, Elaine M, Almouzni, Geneviève, Karpen, Gary H
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127096/
https://ncbi.nlm.nih.gov/pubmed/21738837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.2.15211
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