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Cloning and characterization of an eDNA derived gene cluster that encodes the biosynthesis of the antitumor substance BE-54017

Soil is predicted to contain thousands of unique bacterial species per gram. Soil DNA libraries represent large reservoirs of biosynthetic diversity from which diverse secondary metabolite gene clusters can be recovered and studied. The screening of an archived soil DNA library using primers designe...

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Main Authors: Chang, Fang-Yuan, Brady, Sean F.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126909/
https://ncbi.nlm.nih.gov/pubmed/21542592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2022653
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