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P2Y2 RECEPTORS AND GRK2 ARE INVOLVED IN OSCILLATORY FLUID FLOW INDUCED ERK1/2 RESPONSES IN CHONDROCYTES

Mechanical loading is an important factor regulating cartilage metabolism maintained by chondrocytes. However, some of its underlying mechanisms remain poorly understood. In this study, we employed a chondrogenic cell line ATDC5 to investigate roles of P2Y(2) and GRK2 in chondrocyte mechanotransduct...

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Detalhes bibliográficos
Main Authors: Xing, Yanghui, Gu, Yan, Gomes, Ronald R., You, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126889/
https://ncbi.nlm.nih.gov/pubmed/21520257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21319
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