RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site

Without the RAD51 strand exchange protein, Saccharomyces cerevisiae cannot repair a double-strand break (DSB) by gene conversion. However, cells can repair DSBs by recombination-dependent, break-induced replication (BIR). RAD51-independent BIR is initiated more than 13 kb from the DSB. Repair depend...

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Bibliographische Detailangaben
Hauptverfasser: Malkova, Anna, Signon, Laurence, Schaefer, Christopher B., Naylor, Maria L., Theis, James F., Newlon, Carol S., Haber, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2001
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC312680/
https://ncbi.nlm.nih.gov/pubmed/11331601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.875901
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