Conversion of a gene-specific repressor to a regional silencer
In Saccharomyces cerevisiae, gene silencing at the HMR and HML loci is normally dependent on Sir2p, Sir3p, and Sir4p, which are structural components of silenced chromatin. Sir2p is a NAD+-dependent histone deacetylase required for silencing. Silencing can be restored in cells lacking Sir proteins b...
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| Pubblicato in: | Genes Dev |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2001
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312676/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11316790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.873601 |
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