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SULF-2: AN EXTRACELLULAR MODULATOR OF CELL SIGNALING AND A CANCER TARGET CANDIDATE
IMPORTANCE OF THE FIELD: Sulf-1and Sulf-2 are sulfatases that edit the sulfation status of heparan sulfate proteoglycans (HSPGs) on the outside of cells and regulate a number of critical signaling pathways. The Sulfs are dysregulated in many cancers with Sulf-2 in particular implicated as a driver o...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3126665/ https://ncbi.nlm.nih.gov/pubmed/20629619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2010.504718 |
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