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Protective Effects of Fresh Frozen Plasma on Vascular Endothelial Permeability, Coagulation, and Resuscitation After Hemorrhagic Shock Are Time Dependent and Diminish Between Days 0 and 5 After Thaw

BACKGROUND: Clinical studies have shown that resuscitation with fresh frozen plasma (FFP) is associated with improved outcome after severe hemorrhagic shock (HS). We hypothesized that in addition to its effects on hemostasis, FFP has protective and stabilizing effects on the endothelium that transla...

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Main Authors: Pati, Shibani, Matijevic, Nena, Doursout, Marie-Françoise, Ko, Tien, Cao, Yanna, Deng, Xiyun, Kozar, Rosemary A., Hartwell, Elizabeth, Conyers, Jodie, Holcomb, John B.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126659/
https://ncbi.nlm.nih.gov/pubmed/20622621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e3181e453d4
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