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Pharmacologic Specificity of Nicotinic Receptor-Mediated Relaxation of Muscarinic Receptor Precontracted Human Gastric Clasp and Sling Muscle Fibers within the Gastroesophageal Junction

Relaxation of gastric clasp and sling muscle fibers is involved the transient lower esophageal sphincter relaxations underlying the pathophysiology of gastroesophageal reflux disease (GERD). These fibers do not contribute tone to the high-pressure zone in GERD patients, indicating their role in path...

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Главные авторы: Braverman, Alan S., Vegesna, Anil K., Miller, Larry S., Barbe, Mary F., Tiwana, Mansoor, Hussain, Kashif, Ruggieri, Michael R.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126643/
https://ncbi.nlm.nih.gov/pubmed/21464333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.177097
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