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HIV Gag-Leucine Zipper Chimeras Form ABCE1-Containing Intermediates and RNase-Resistant Immature Capsids Similar to Those Formed by Wild-Type HIV-1 Gag

During HIV-1 assembly, Gag polypeptides multimerize to form an immature capsid and also package HIV-1 genomic RNA. Assembling Gag forms immature capsids by progressing through a stepwise pathway of assembly intermediates containing the cellular ATPase ABCE1, which facilitates capsid formation. The N...

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Autors principals: Klein, Kevin C., Reed, Jonathan C., Tanaka, Motoko, Nguyen, Veronica T., Giri, Samina, Lingappa, Jaisri R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126549/
https://ncbi.nlm.nih.gov/pubmed/21543480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00288-11
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