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Detection of Chronic Wasting Disease Prions in Salivary, Urinary, and Intestinal Tissues of Deer: Potential Mechanisms of Prion Shedding and Transmission

Efficient horizontal transmission is a signature trait of chronic wasting disease (CWD) in cervids. Infectious prions shed into excreta appear to play a key role in this facile transmission, as has been demonstrated by bioassays of cervid and transgenic species and serial protein misfolding cyclic a...

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Detalhes bibliográficos
Main Authors: Haley, Nicholas J., Mathiason, Candace K., Carver, Scott, Zabel, Mark, Telling, Glenn C., Hoover, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126547/
https://ncbi.nlm.nih.gov/pubmed/21525361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00425-11
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