Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family

The activity of the DAF-2 insulin-like receptor is required for Caenorhabditis elegans reproductive growth and normal adult life span. Informatic analysis identified 37 C. elegans genes predicted to encode insulin-like peptides. Many of these genes are divergent insulin superfamily members, and many...

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Pubblicato in:	Genes Dev
Autori principali:	Pierce, Sarah B., Costa, Michael, Wisotzkey, Robert, Devadhar, Sharmila, Homburger, Sheila A., Buchman, Andrew R., Ferguson, Kimberly C., Heller, Jonathan, Platt, Darren M., Pasquinelli, Amy A., Liu, Leo X., Doberstein, Stephen K., Ruvkun, Gary
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2001
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312654/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.867301
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