Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability

Noroviruses are the dominant cause of outbreaks of gastroenteritis worldwide, and interactions with human histo-blood group antigens (HBGAs) are thought to play a critical role in their entry mechanism. Structures of noroviruses from genogroups GI and GII in complex with HBGAs, however, reveal diffe...

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Detalhes bibliográficos
Main Authors: Hansman, Grant S., Biertümpfel, Christian, Georgiev, Ivelin, McLellan, Jason S., Chen, Lei, Zhou, Tongqing, Katayama, Kazuhiko, Kwong, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126497/
https://ncbi.nlm.nih.gov/pubmed/21525337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-11
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