Versatile Enzyme Expression and Characterization System for Aspergillus nidulans, with the Penicillium brevicompactum Polyketide Synthase Gene from the Mycophenolic Acid Gene Cluster as a Test Case

Assigning functions to newly discovered genes constitutes one of the major challenges en route to fully exploiting the data becoming available from the genome sequencing initiatives. Heterologous expression in an appropriate host is central in functional genomics studies. In this context, filamentou...

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Main Authors: Hansen, Bjarne G., Salomonsen, Bo, Nielsen, Morten T., Nielsen, Jakob B., Hansen, Niels B., Nielsen, Kristian F., Regueira, Torsten B., Nielsen, Jens, Patil, Kiran R., Mortensen, Uffe H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126399/
https://ncbi.nlm.nih.gov/pubmed/21398493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01768-10
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