A model for the abrogation of the SOS response by an SOS protein: a negatively charged helix in DinI mimics DNA in its interaction with RecA

DinI is a recently described negative regulator of the SOS response in Escherichia coli. Here we show that it physically interacts with RecA and prevents the binding of single-stranded DNA to RecA, which is required for the activation of the latter. DinI also displaces ssDNA from a stable RecA–DNA c...

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Detaylı Bibliyografya
Asıl Yazarlar: Voloshin, Oleg N., Ramirez, Benjamin E., Bax, Ad, Camerini-Otero, R. Daniel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2001
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC312637/
https://ncbi.nlm.nih.gov/pubmed/11230150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.862901
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