A model for the abrogation of the SOS response by an SOS protein: a negatively charged helix in DinI mimics DNA in its interaction with RecA

DinI is a recently described negative regulator of the SOS response in Escherichia coli. Here we show that it physically interacts with RecA and prevents the binding of single-stranded DNA to RecA, which is required for the activation of the latter. DinI also displaces ssDNA from a stable RecA–DNA c...

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Veröffentlicht in:	Genes Dev
Hauptverfasser:	Voloshin, Oleg N., Ramirez, Benjamin E., Bax, Ad, Camerini-Otero, R. Daniel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Cold Spring Harbor Laboratory Press 2001
Schlagworte:	Research Paper
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230150/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.862901
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