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Cdc13 both positively and negatively regulates telomere replication

Cdc13 is a single-strand telomeric DNA-binding protein that positively regulates yeast telomere replication by recruiting telomerase to chromosome termini through a site on Cdc13 that is eliminated by the cdc13-2 mutation. Here we show that Cdc13 has a separate role in negative regulation of telomer...

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書目詳細資料
Main Authors: Chandra, Abha, Hughes, Timothy R., Nugent, Constance I., Lundblad, Victoria
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC312634/
https://ncbi.nlm.nih.gov/pubmed/11230149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.861001
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