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Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-d-Aspartate Receptor 2C (NR2C) ‡

Phox (PX) domain-containing sorting nexins (SNXs) are emerging as important regulators of endocytic trafficking. Sorting nexin 27 (SNX27) is unique, as it contains a PDZ (Psd-95/Dlg/ZO1) domain. We show here that SNX27 is primarily targeted to the early endosome by interaction of its PX domain with...

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Autors principals: Cai, Lei, Loo, Li Shen, Atlashkin, Vadim, Hanson, Brendon J., Hong, Wanjin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126336/
https://ncbi.nlm.nih.gov/pubmed/21300787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01044-10
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