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A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus

Herpes simplex virus (HSV) entry requires host cell 26S proteasomal degradation activity at a postpenetration step. When expressed in the infected cell, the HSV immediate-early protein ICP0 has E3 ubiquitin ligase activity and interacts with the proteasome. The cell is first exposed to ICP0 during v...

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Библиографические подробности
Главные авторы: Delboy, Mark G., Nicola, Anthony V.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126318/
https://ncbi.nlm.nih.gov/pubmed/21471243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00267-11
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