Receptor-Ligand Requirements for Increased NK Cell Polyfunctional Potential in Slow Progressors Infected with HIV-1 Coexpressing KIR3DL1*h/*y and HLA-B*57

Carriage of the natural killer (NK) receptor genotype KIR3DL1*h/*y with its HLA-B*57 ligand (*h/*y+B*57) is associated with slow time to AIDS and low viral load (VL). To provide a functional basis for these epidemiological observations, we assessed whether HIV-1-infected slow progressors (SP) carryi...

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Detalhes bibliográficos
Main Authors: Kamya, Philomena, Boulet, Salix, Tsoukas, Christos M., Routy, Jean-Pierre, Thomas, Réjean, Côté, Pierre, Boulassel, Mohamed-Rachid, Baril, Jean-Guy, Kovacs, Colin, Migueles, Stephen A., Connors, Mark, Suscovich, Todd J., Brander, Christian, Tremblay, Cecile L., Bernard, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126301/
https://ncbi.nlm.nih.gov/pubmed/21471235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02652-10
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