The Role of LAT in Increased CD8(+) T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1

Herpes simplex virus (HSV) infection is a classic example of latent viral infection in humans and experimental animal models. The HSV-1 latency-associated transcript (LAT) plays a major role in the HSV-1 latency reactivation cycle and thus in recurrent disease. Whether the presence of LAT leads to g...

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Hlavní autoři: Allen, Sariah J., Hamrah, Pedram, Gate, David, Mott, Kevin R., Mantopoulos, Dimosthenis, Zheng, Lixin, Town, Terrence, Jones, Clinton, von Andrian, Ulrich H., Freeman, Gordon J., Sharpe, Arlene H., BenMohamed, Lbachir, Ahmed, Rafi, Wechsler, Steven L., Ghiasi, Homayon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126262/
https://ncbi.nlm.nih.gov/pubmed/21307196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02290-10
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